The talk will take a brisk survey of the theme of Cooperation and Competition in U.S.-China Relations as viewed from three different timeframes: (1) the historical perspective over the most recent 100 years (which will be referenced extremely lightly since it is familiar territory for the Helen T. Lin Legacy audience); (2) the 'recent history' perspective of the past 20 years will contrast the two strands through my professional work -- the 10-year Framework effort launched by Hank Paulson and expanded by the Obama Administration for cooperation with China in energy, environment and climate change mitigation and the fraught competitive issue, which has waxed and waned, involving semiconductors, microchip supply chains and advanced technologies; and (3) a brief state-of-play analysis of where things stand in my view at the current moment at the national level with Biden Administration policies but also touching on sub-national and people-to-people dynamics.